L328-0493 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide

L328-0493 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide
L328-0493 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L328-0493
1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L328-0493

Molecular Formula

C25H34FN5O3 (C25 H34 FN5 O3)

Compound Name

1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide

IUPAC name

1-(13-dimethyl-26-dioxo-1236-tetrahydropyrimidin-4-yl)-N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)piperidine-3-carboxamide

SMILES

CN(C(C=C(N1C)N(CCC2)CC2C(NCC2CCN(Cc(cc3)ccc3F)CC2)=O)=O)C1=O

InChI

InChI=1S/C25H34FN5O3/c1-28-22(14-23(32)29(2)25(28)34)31-11-3-4-20(17-31)24(33)27-15-18-9-12-30(13-10-18)16-19-5-7-21(26)8-6-19/h5-8,14,18,20H,3-4,9-13,15-17H2,1-2H3,(H,27,33)/t20-/m0/s1

InChI Key

SHRGPMLGBWNUOJ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27246195

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.119

Distribution Coefficient, logD

0.329

Water Solubility, LogSw

-2.73

Polar Surface Area

63.804

Acid Dissociation Constant (pKa)

14.08

Base Dissociation Constant (pKb)

9.18

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

56.00

L328-0493 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L328-0493 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L328-0493?
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What is the minimum amount of L328-0493 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L328-0493
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L328-0493
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L328-0493 available by request