L328-0550 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]piperidine-3-carboxamide

L328-0550 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]piperidine-3-carboxamide
L328-0550 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L328-0550
1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L328-0550

Molecular Formula

C22H30N4O6 (C22 H30 N4 O6)

Compound Name

1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N-[(3,4,5-trimethoxyphenyl)methyl]piperidine-3-carboxamide

IUPAC name

1-(13-dimethyl-26-dioxo-1236-tetrahydropyrimidin-4-yl)-N-[(345-trimethoxyphenyl)methyl]piperidine-3-carboxamide

SMILES

CN(C(C=C(N1C)N(CCC2)CC2C(NCc(cc2OC)cc(OC)c2OC)=O)=O)C1=O

InChI

InChI=1S/C22H30N4O6/c1-24-18(11-19(27)25(2)22(24)29)26-8-6-7-15(13-26)21(28)23-12-14-9-16(30-3)20(32-5)17(10-14)31-4/h9-11,15H,6-8,12-13H2,1-5H3,(H,23,28)/t15-/m0/s1

InChI Key

ZHMRZAKDDZEXEP-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27246210

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.923

Distribution Coefficient, logD

0.923

Water Solubility, LogSw

-1.83

Polar Surface Area

83.049

Acid Dissociation Constant (pKa)

14.50

Base Dissociation Constant (pKb)

0.85

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

50.00

L328-0550 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L328-0550 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L328-0550?
Check Price and Availability of L328-0550, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L328-0550 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L328-0550
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L328-0550
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L328-0550 available by request