L329-0177 Screening compound: 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0177 Screening compound: 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0177 Screening compound: 6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0177
6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0177

Molecular Formula

C19H24N4O5 (C19 H24 N4 O5)

Compound Name

6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-[4-(34-dimethoxybenzoyl)piperazin-1-yl]-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C=C(N1C)N(CC2)CCN2C(c(cc2)cc(OC)c2OC)=O)=O)C1=O

InChI

InChI=1S/C19H24N4O5/c1-20-16(12-17(24)21(2)19(20)26)22-7-9-23(10-8-22)18(25)13-5-6-14(27-3)15(11-13)28-4/h5-6,11-12H,7-10H2,1-4H3

InChI Key

PCULPINMUJBGQL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246222

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.42

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.475

Distribution Coefficient, logD

0.475

Water Solubility, LogSw

-1.63

Polar Surface Area

67.441

Acid Dissociation Constant (pKa)

29.11

Base Dissociation Constant (pKb)

-2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

L329-0177 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS MPO Library (28609 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L329-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0177?
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What is the minimum amount of L329-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0177 available by request