L329-0250 Screening compound: 1,3-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0250 Screening compound: 1,3-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0250 Screening compound: 1,3-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0250
1,3-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0250

Molecular Formula

C19H24N4O4 (C19 H24 N4 O4)

Compound Name

1,3-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

13-dimethyl-6-{4-[2-(3-methylphenoxy)acetyl]piperazin-1-yl}-1234-tetrahydropyrimidine-24-dione

SMILES

Cc1cccc(OCC(N(CC2)CCN2C(N(C)C(N2C)=O)=CC2=O)=O)c1

InChI

InChI=1S/C19H24N4O4/c1-14-5-4-6-15(11-14)27-13-18(25)23-9-7-22(8-10-23)16-12-17(24)21(3)19(26)20(16)2/h4-6,11-12H,7-10,13H2,1-3H3

InChI Key

SYDWXVJDPDKJOL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246267

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

372.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.207

Distribution Coefficient, logD

1.207

Water Solubility, LogSw

-1.73

Polar Surface Area

59.152

Acid Dissociation Constant (pKa)

25.23

Base Dissociation Constant (pKb)

-0.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

L329-0250 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with L329-0250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0250?
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What is the minimum amount of L329-0250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0250 available by request