L329-0268 Screening compound: 6-(4-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0268 Screening compound: 6-(4-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0268 Screening compound: 6-(4-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0268
6-(4-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0268

Molecular Formula

C23H26N6O4 (C23 H26 N6 O4)

Compound Name

6-(4-{7-methoxy-1H,4H,5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-(4-{7-methoxy-1H4H5H-benzo[g]indazole-3-carbonyl}piperazin-1-yl)-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C=C(N1C)N(CC2)CCN2C(c2n[nH]c-3c2CCc2c3ccc(OC)c2)=O)=O)C1=O

InChI

InChI=1S/C23H26N6O4/c1-26-18(13-19(30)27(2)23(26)32)28-8-10-29(11-9-28)22(31)21-17-6-4-14-12-15(33-3)5-7-16(14)20(17)24-25-21/h5,7,12-13H,4,6,8-11H2,1-3H3,(H,24,25)

InChI Key

YCOJHKJVAMUJGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246277

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.026

Distribution Coefficient, logD

2.026

Water Solubility, LogSw

-2.88

Polar Surface Area

83.766

Acid Dissociation Constant (pKa)

6.65

Base Dissociation Constant (pKb)

-0.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L329-0268 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Immune system
Mechanism of action:
  • PPI modulators
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L329-0268 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0268?
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What is the minimum amount of L329-0268 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0268
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0268
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0268 available by request