L329-0279 Screening compound: 6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0279 Screening compound: 6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0279 Screening compound: 6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0279
6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0279

Molecular Formula

C20H23N5O4 (C20 H23 N5 O4)

Compound Name

6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-[4-(6-methoxy-1H-indole-2-carbonyl)piperazin-1-yl]-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C=C(N1C)N(CC2)CCN2C(c2cc(ccc(OC)c3)c3[nH]2)=O)=O)C1=O

InChI

InChI=1S/C20H23N5O4/c1-22-17(12-18(26)23(2)20(22)28)24-6-8-25(9-7-24)19(27)16-10-13-4-5-14(29-3)11-15(13)21-16/h4-5,10-12,21H,6-9H2,1-3H3

InChI Key

HROPHXJVAKHNQI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246283

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.975

Distribution Coefficient, logD

1.975

Water Solubility, LogSw

-2.91

Polar Surface Area

69.073

Acid Dissociation Constant (pKa)

15.22

Base Dissociation Constant (pKb)

-0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.00

L329-0279 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Indole Derivatives (10091 compounds)

Nucleic Acid Ligands (8311 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L329-0279 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0279?
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What is the minimum amount of L329-0279 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0279
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0279
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0279 available by request