L329-0515 Screening compound: 6-[4-(4-bromobenzoyl)-1,4-diazepan-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0515 Screening compound: 6-[4-(4-bromobenzoyl)-1,4-diazepan-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0515 Screening compound: 6-[4-(4-bromobenzoyl)-1,4-diazepan-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0515
6-[4-(4-bromobenzoyl)-1,4-diazepan-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0515

Molecular Formula

C18H21BrN4O3 (C18 H21 BrN4 O3)

Compound Name

6-[4-(4-bromobenzoyl)-1,4-diazepan-1-yl]-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-[4-(4-bromobenzoyl)-14-diazepan-1-yl]-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C=C(N1C)N(CCC2)CCN2C(c(cc2)ccc2Br)=O)=O)C1=O

InChI

InChI=1S/C18H21BrN4O3/c1-20-15(12-16(24)21(2)18(20)26)22-8-3-9-23(11-10-22)17(25)13-4-6-14(19)7-5-13/h4-7,12H,3,8-11H2,1-2H3

InChI Key

JUKXPPWCHIDLKP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246319

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.29

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.037

Distribution Coefficient, logD

2.037

Water Solubility, LogSw

-2.31

Polar Surface Area

52.511

Acid Dissociation Constant (pKa)

27.80

Base Dissociation Constant (pKb)

-1.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.90

L329-0515 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L329-0515 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0515?
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What is the minimum amount of L329-0515 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0515
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0515
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0515 available by request