L329-0670 Screening compound: 6-[4-(3-methylbenzoyl)piperazin-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0670 Screening compound: 6-[4-(3-methylbenzoyl)piperazin-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0670 Screening compound: 6-[4-(3-methylbenzoyl)piperazin-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0670
6-[4-(3-methylbenzoyl)piperazin-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0670

Molecular Formula

C22H30N4O3 (C22 H30 N4 O3)

Compound Name

6-[4-(3-methylbenzoyl)piperazin-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-[4-(3-methylbenzoyl)piperazin-1-yl]-13-bis(propan-2-yl)-1234-tetrahydropyrimidine-24-dione

SMILES

CC(C)N(C(C=C(N(CC1)CCN1C(c1cc(C)ccc1)=O)N1C(C)C)=O)C1=O

InChI

InChI=1S/C22H30N4O3/c1-15(2)25-19(14-20(27)26(16(3)4)22(25)29)23-9-11-24(12-10-23)21(28)18-8-6-7-17(5)13-18/h6-8,13-16H,9-12H2,1-5H3

InChI Key

PJYMFVNANNSTCM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246373

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.611

Distribution Coefficient, logD

2.611

Water Solubility, LogSw

-2.67

Polar Surface Area

52.090

Acid Dissociation Constant (pKa)

28.03

Base Dissociation Constant (pKb)

-1.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L329-0670 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L329-0670 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0670?
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What is the minimum amount of L329-0670 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0670
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0670
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0670 available by request