L329-0779 Screening compound: 6-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

L329-0779 Screening compound: 6-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
L329-0779 Screening compound: 6-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L329-0779
6-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L329-0779

Molecular Formula

C22H29ClN4O3 (C22 H29 ClN4 O3)

Compound Name

6-[4-(3-chlorobenzoyl)-1,4-diazepan-1-yl]-1,3-bis(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-[4-(3-chlorobenzoyl)-14-diazepan-1-yl]-13-bis(propan-2-yl)-1234-tetrahydropyrimidine-24-dione

SMILES

CC(C)N(C(C=C(N1C(C)C)N(CCC2)CCN2C(c2cccc(Cl)c2)=O)=O)C1=O

InChI

InChI=1S/C22H29ClN4O3/c1-15(2)26-19(14-20(28)27(16(3)4)22(26)30)24-9-6-10-25(12-11-24)21(29)17-7-5-8-18(23)13-17/h5,7-8,13-16H,6,9-12H2,1-4H3

InChI Key

XDSKFIXWYXHNSD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246443

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.95

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.171

Distribution Coefficient, logD

3.171

Water Solubility, LogSw

-3.44

Polar Surface Area

52.421

Acid Dissociation Constant (pKa)

27.80

Base Dissociation Constant (pKb)

-1.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L329-0779 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L329-0779 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L329-0779?
Check Price and Availability of L329-0779, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L329-0779 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L329-0779
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L329-0779
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L329-0779 available by request