L331-0214 Screening compound: ethyl 4-{[(4-morpholino[1]benzofuro[3,2-d]pyrimidin-2-yl)carbonyl]amino}benzoate

L331-0214 Screening compound: ethyl 4-{[(4-morpholino[1]benzofuro[3,2-d]pyrimidin-2-yl)carbonyl]amino}benzoate
L331-0214 Screening compound: ethyl 4-{[(4-morpholino[1]benzofuro[3,2-d]pyrimidin-2-yl)carbonyl]amino}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L331-0214
ethyl 4-{[(4-morpholino[1]benzofuro[3,2-d]pyrimidin-2-yl)carbonyl]amino}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L331-0214

Molecular Formula

C24H22N4O5 (C24 H22 N4 O5)

Compound Name

ethyl 4-{[(4-morpholino[1]benzofuro[3,2-d]pyrimidin-2-yl)carbonyl]amino}benzoate

IUPAC name

ethyl 4-[6-(morpholin-4-yl)-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)35911-hexaene-4-amido]benzoate

SMILES

CCOC(c(cc1)ccc1NC(c1nc(N2CCOCC2)c2oc(cccc3)c3c2n1)=O)=O

InChI

InChI=1S/C24H22N4O5/c1-2-32-24(30)15-7-9-16(10-8-15)25-23(29)21-26-19-17-5-3-4-6-18(17)33-20(19)22(27-21)28-11-13-31-14-12-28/h3-10H,2,11-14H2,1H3,(H,25,29)

InChI Key

GCYOLMDGSPUDET-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27643811

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.46

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.622

Distribution Coefficient, logD

4.622

Water Solubility, LogSw

-4.18

Polar Surface Area

82.853

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

8.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L331-0214 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with L331-0214 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L331-0214?
Check Price and Availability of L331-0214, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L331-0214 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L331-0214
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L331-0214
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L331-0214 available by request