L331-0267 Screening compound: N~2~-cyclohexyl-4-morpholino[1]benzofuro[3,2-d]pyrimidine-2-carboxamide

L331-0267 Screening compound: N~2~-cyclohexyl-4-morpholino[1]benzofuro[3,2-d]pyrimidine-2-carboxamide
L331-0267 Screening compound: N~2~-cyclohexyl-4-morpholino[1]benzofuro[3,2-d]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L331-0267
N~2~-cyclohexyl-4-morpholino[1]benzofuro[3,2-d]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L331-0267

Molecular Formula

C21H24N4O3 (C21 H24 N4 O3)

Compound Name

N~2~-cyclohexyl-4-morpholino[1]benzofuro[3,2-d]pyrimidine-2-carboxamide

IUPAC name

N-cyclohexyl-6-(morpholin-4-yl)-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(13)2(7)35911-hexaene-4-carboxamide

SMILES

O=C(c1nc(N2CCOCC2)c2oc(cccc3)c3c2n1)NC1CCCCC1

InChI

InChI=1S/C21H24N4O3/c26-21(22-14-6-2-1-3-7-14)19-23-17-15-8-4-5-9-16(15)28-18(17)20(24-19)25-10-12-27-13-11-25/h4-5,8-9,14H,1-3,6-7,10-13H2,(H,22,26)

InChI Key

ZZWOCROJGFGWJQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27246927

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

380.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.053

Distribution Coefficient, logD

4.053

Water Solubility, LogSw

-4.12

Polar Surface Area

63.147

Acid Dissociation Constant (pKa)

15.73

Base Dissociation Constant (pKb)

2.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.60

L331-0267 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L331-0267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L331-0267?
Check Price and Availability of L331-0267, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L331-0267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L331-0267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L331-0267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L331-0267 available by request