L333-0216 Screening compound: N-cyclohexyl-4-{2-[(2,4-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide

L333-0216 Screening compound: N-cyclohexyl-4-{2-[(2,4-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide
L333-0216 Screening compound: N-cyclohexyl-4-{2-[(2,4-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L333-0216
N-cyclohexyl-4-{2-[(2,4-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L333-0216

Molecular Formula

C23H35N3O4 (C23 H35 N3 O4)

Compound Name

N-cyclohexyl-4-{2-[(2,4-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide

IUPAC name

N-cyclohexyl-4-{2-[(24-dimethoxyphenyl)formamido]ethyl}piperidine-1-carboxamide

SMILES

COc(cc1)cc(OC)c1C(NCCC(CC1)CCN1C(NC1CCCCC1)=O)=O

InChI

InChI=1S/C23H35N3O4/c1-29-19-8-9-20(21(16-19)30-2)22(27)24-13-10-17-11-14-26(15-12-17)23(28)25-18-6-4-3-5-7-18/h8-9,16-18H,3-7,10-15H2,1-2H3,(H,24,27)(H,25,28)

InChI Key

XDMKRJHIOMAALE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124596

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.55

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.965

Distribution Coefficient, logD

3.965

Water Solubility, LogSw

-4.22

Polar Surface Area

66.184

Acid Dissociation Constant (pKa)

11.91

Base Dissociation Constant (pKb)

2.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

65.20

L333-0216 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L333-0216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L333-0216?
Check Price and Availability of L333-0216, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L333-0216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L333-0216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L333-0216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L333-0216 available by request