L333-0309 Screening compound: 4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide

L333-0309 Screening compound: 4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide
L333-0309 Screening compound: 4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L333-0309
4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L333-0309

Molecular Formula

C24H31N3O3 (C24 H31 N3 O3)

Compound Name

4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide

IUPAC name

4-{2-[2-(3-methoxyphenyl)acetamido]ethyl}-N-(3-methylphenyl)piperidine-1-carboxamide

SMILES

Cc1cccc(NC(N2CCC(CCNC(Cc3cc(OC)ccc3)=O)CC2)=O)c1

InChI

InChI=1S/C24H31N3O3/c1-18-5-3-7-21(15-18)26-24(29)27-13-10-19(11-14-27)9-12-25-23(28)17-20-6-4-8-22(16-20)30-2/h3-8,15-16,19H,9-14,17H2,1-2H3,(H,25,28)(H,26,29)

InChI Key

JATYZMIDLBEEMF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28994054

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.503

Distribution Coefficient, logD

3.503

Water Solubility, LogSw

-3.71

Polar Surface Area

57.293

Acid Dissociation Constant (pKa)

13.77

Base Dissociation Constant (pKb)

-0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

L333-0309 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L333-0309 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L333-0309?
Check Price and Availability of L333-0309, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L333-0309 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L333-0309
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L333-0309
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L333-0309 available by request