L334-2358 Screening compound: N-(2,5-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide

L334-2358 Screening compound: N-(2,5-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide
L334-2358 Screening compound: N-(2,5-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L334-2358
N-(2,5-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L334-2358

Molecular Formula

C20H25F2N5O2 (C20 H25 F2 N5 O2)

Compound Name

N-(2,5-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide

IUPAC name

N-(25-difluorophenyl)-4-{2-[(1-ethyl-1H-pyrazol-5-yl)formamido]ethyl}piperidine-1-carboxamide

SMILES

CCn1nccc1C(NCCC(CC1)CCN1C(Nc(cc(cc1)F)c1F)=O)=O

InChI

InChI=1S/C20H25F2N5O2/c1-2-27-18(6-10-24-27)19(28)23-9-5-14-7-11-26(12-8-14)20(29)25-17-13-15(21)3-4-16(17)22/h3-4,6,10,13-14H,2,5,7-9,11-12H2,1H3,(H,23,28)(H,25,29)

InChI Key

NVZDJQNJJNDYPD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29008759

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.717

Distribution Coefficient, logD

2.716

Water Solubility, LogSw

-3.10

Polar Surface Area

62.354

Acid Dissociation Constant (pKa)

10.26

Base Dissociation Constant (pKb)

0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

L334-2358 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antiviral Library (67538 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L334-2358 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L334-2358?
Check Price and Availability of L334-2358, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L334-2358 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L334-2358
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L334-2358
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L334-2358 available by request