L334-2411 Screening compound: N-(2-{1-[(2,5-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide

L334-2411 Screening compound: N-(2-{1-[(2,5-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide
L334-2411 Screening compound: N-(2-{1-[(2,5-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L334-2411
N-(2-{1-[(2,5-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L334-2411

Molecular Formula

C19H21F2N5O2 (C19 H21 F2 N5 O2)

Compound Name

N-(2-{1-[(2,5-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide

IUPAC name

N-(2-{1-[(25-difluorophenyl)carbamoyl]piperidin-4-yl}ethyl)pyrazine-2-carboxamide

SMILES

O=C(c1nccnc1)NCCC(CC1)CCN1C(Nc(cc(cc1)F)c1F)=O

InChI

InChI=1S/C19H21F2N5O2/c20-14-1-2-15(21)16(11-14)25-19(28)26-9-4-13(5-10-26)3-6-24-18(27)17-12-22-7-8-23-17/h1-2,7-8,11-13H,3-6,9-10H2,(H,24,27)(H,25,28)

InChI Key

LEWLTYPATZIBOX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29007769

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.243

Distribution Coefficient, logD

2.243

Water Solubility, LogSw

-2.56

Polar Surface Area

67.830

Acid Dissociation Constant (pKa)

10.26

Base Dissociation Constant (pKb)

-0.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

L334-2411 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L334-2411 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L334-2411?
Check Price and Availability of L334-2411, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L334-2411 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L334-2411
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L334-2411
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L334-2411 available by request