L334-2558 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(2,4-difluorophenyl)piperidine-1-carboxamide

L334-2558 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(2,4-difluorophenyl)piperidine-1-carboxamide
L334-2558 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(2,4-difluorophenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L334-2558
4-[2-(cyclopentylformamido)ethyl]-N-(2,4-difluorophenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L334-2558

Molecular Formula

C20H27F2N3O2 (C20 H27 F2 N3 O2)

Compound Name

4-[2-(cyclopentylformamido)ethyl]-N-(2,4-difluorophenyl)piperidine-1-carboxamide

IUPAC name

4-[2-(cyclopentylformamido)ethyl]-N-(24-difluorophenyl)piperidine-1-carboxamide

SMILES

O=C(C1CCCC1)NCCC(CC1)CCN1C(Nc(ccc(F)c1)c1F)=O

InChI

InChI=1S/C20H27F2N3O2/c21-16-5-6-18(17(22)13-16)24-20(27)25-11-8-14(9-12-25)7-10-23-19(26)15-3-1-2-4-15/h5-6,13-15H,1-4,7-12H2,(H,23,26)(H,24,27)

InChI Key

NCYCQNRUYYGUBN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29007830

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

379.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.660

Distribution Coefficient, logD

3.660

Water Solubility, LogSw

-3.85

Polar Surface Area

49.823

Acid Dissociation Constant (pKa)

10.34

Base Dissociation Constant (pKb)

0.60

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

L334-2558 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Bcl2-PPI Inhibitors Library (12246 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
  • Mimetics
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L334-2558 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L334-2558?
Check Price and Availability of L334-2558, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L334-2558 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L334-2558
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L334-2558
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L334-2558 available by request