L334-2648 Screening compound: N-(3,5-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide

L334-2648 Screening compound: N-(3,5-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide
L334-2648 Screening compound: N-(3,5-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L334-2648
N-(3,5-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L334-2648

Molecular Formula

C18H25F2N3O3 (C18 H25 F2 N3 O3)

Compound Name

N-(3,5-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide

IUPAC name

N-(35-difluorophenyl)-4-[2-(3-methoxypropanamido)ethyl]piperidine-1-carboxamide

SMILES

COCCC(NCCC(CC1)CCN1C(Nc1cc(F)cc(F)c1)=O)=O

InChI

InChI=1S/C18H25F2N3O3/c1-26-9-5-17(24)21-6-2-13-3-7-23(8-4-13)18(25)22-16-11-14(19)10-15(20)12-16/h10-13H,2-9H2,1H3,(H,21,24)(H,22,25)

InChI Key

JRZOFRHQKJPUNV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD29008484

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.043

Distribution Coefficient, logD

2.043

Water Solubility, LogSw

-2.75

Polar Surface Area

58.363

Acid Dissociation Constant (pKa)

10.27

Base Dissociation Constant (pKb)

3.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

55.60

L334-2648 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cancer
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L334-2648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L334-2648?
Check Price and Availability of L334-2648, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L334-2648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L334-2648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L334-2648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L334-2648 available by request