L334-2791 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide

L334-2791 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide
L334-2791 Screening compound: 4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L334-2791
4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L334-2791

Molecular Formula

C21H30FN3O2 (C21 H30 FN3 O2)

Compound Name

4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide

IUPAC name

4-[2-(cyclopentylformamido)ethyl]-N-(3-fluoro-4-methylphenyl)piperidine-1-carboxamide

SMILES

Cc(ccc(NC(N1CCC(CCNC(C2CCCC2)=O)CC1)=O)c1)c1F

InChI

InChI=1S/C21H30FN3O2/c1-15-6-7-18(14-19(15)22)24-21(27)25-12-9-16(10-13-25)8-11-23-20(26)17-4-2-3-5-17/h6-7,14,16-17H,2-5,8-13H2,1H3,(H,23,26)(H,24,27)

InChI Key

AZJMUJXYWFCFBA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD31993156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

375.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.998

Distribution Coefficient, logD

3.998

Water Solubility, LogSw

-4.10

Polar Surface Area

50.521

Acid Dissociation Constant (pKa)

12.02

Base Dissociation Constant (pKb)

-1.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.90

L334-2791 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

PPI Helix Turn 3D-Mimetics Library (71298 compounds)

Protein-Protein Interaction Library (218420 compounds)

Alpha-Helix Mimetics Library (25899 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L334-2791 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L334-2791?
Check Price and Availability of L334-2791, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L334-2791 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L334-2791
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L334-2791
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L334-2791 available by request