L337-0205 Screening compound: 1-(3,4-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

L337-0205 Screening compound: 1-(3,4-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea
L337-0205 Screening compound: 1-(3,4-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L337-0205
1-(3,4-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L337-0205

Molecular Formula

C18H23N5O4S (C18 H23 N5 O4 S)

Compound Name

1-(3,4-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

IUPAC name

1-(34-dimethoxyphenyl)-3-{5-[2-oxo-2-(piperidin-1-yl)ethyl]-134-thiadiazol-2-yl}urea

SMILES

COc(ccc(NC(Nc1nnc(CC(N2CCCCC2)=O)s1)=O)c1)c1OC

InChI

InChI=1S/C18H23N5O4S/c1-26-13-7-6-12(10-14(13)27-2)19-17(25)20-18-22-21-15(28-18)11-16(24)23-8-4-3-5-9-23/h6-7,10H,3-5,8-9,11H2,1-2H3,(H2,19,20,22,25)

InChI Key

BDETZEPDSUZCRM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247065

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.403

Distribution Coefficient, logD

2.402

Water Solubility, LogSw

-3.05

Polar Surface Area

87.963

Acid Dissociation Constant (pKa)

9.97

Base Dissociation Constant (pKb)

0.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

L337-0205 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L337-0205 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L337-0205?
Check Price and Availability of L337-0205, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L337-0205 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L337-0205
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L337-0205
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L337-0205 available by request