L337-0283 Screening compound: 1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

L337-0283 Screening compound: 1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea
L337-0283 Screening compound: 1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L337-0283
1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L337-0283

Molecular Formula

C16H19N5O2S (C16 H19 N5 O2 S)

Compound Name

1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1,3,4-thiadiazol-2-yl}urea

IUPAC name

1-(4-methylphenyl)-3-{5-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-134-thiadiazol-2-yl}urea

SMILES

Cc(cc1)ccc1NC(Nc1nnc(CC(N2CCCC2)=O)s1)=O

InChI

InChI=1S/C16H19N5O2S/c1-11-4-6-12(7-5-11)17-15(23)18-16-20-19-13(24-16)10-14(22)21-8-2-3-9-21/h4-7H,2-3,8-10H2,1H3,(H2,17,18,20,23)

InChI Key

HHNPDQIEQWWQLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247083

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.073

Distribution Coefficient, logD

3.070

Water Solubility, LogSw

-3.36

Polar Surface Area

73.069

Acid Dissociation Constant (pKa)

9.66

Base Dissociation Constant (pKb)

-1.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L337-0283 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L337-0283 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L337-0283?
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What is the minimum amount of L337-0283 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L337-0283
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L337-0283
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L337-0283 available by request