L341-0381 Screening compound: N-[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]-2-[4-(2,4,5-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide

L341-0381 Screening compound: N-[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]-2-[4-(2,4,5-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide
L341-0381 Screening compound: N-[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]-2-[4-(2,4,5-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L341-0381
N-[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]-2-[4-(2,4,5-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L341-0381

Molecular Formula

C24H29N5O3S2 (C24 H29 N5 O3 S2)

Compound Name

N-[5-(3-methylphenyl)-1,3,4-thiadiazol-2-yl]-2-[4-(2,4,5-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide

IUPAC name

N-[5-(3-methylphenyl)-134-thiadiazol-2-yl]-2-[4-(245-trimethylbenzenesulfonyl)piperazin-1-yl]acetamide

SMILES

Cc1cccc(-c2nnc(NC(CN(CC3)CCN3S(c3c(C)cc(C)c(C)c3)(=O)=O)=O)s2)c1

InChI

InChI=1S/C24H29N5O3S2/c1-16-6-5-7-20(12-16)23-26-27-24(33-23)25-22(30)15-28-8-10-29(11-9-28)34(31,32)21-14-18(3)17(2)13-19(21)4/h5-7,12-14H,8-11,15H2,1-4H3,(H,25,27,30)

InChI Key

VITJUPPJEUJYAA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247242

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.66

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.146

Distribution Coefficient, logD

5.146

Water Solubility, LogSw

-4.93

Polar Surface Area

81.913

Acid Dissociation Constant (pKa)

10.68

Base Dissociation Constant (pKb)

2.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L341-0381 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L341-0381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L341-0381?
Check Price and Availability of L341-0381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L341-0381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L341-0381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L341-0381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L341-0381 available by request