L346-0080 Screening compound: N-(2-methoxyethyl)-5-{[(4-methoxyphenyl)sulfonyl]amino}-2-piperazinonicotinamide

L346-0080 Screening compound: N-(2-methoxyethyl)-5-{[(4-methoxyphenyl)sulfonyl]amino}-2-piperazinonicotinamide
L346-0080 Screening compound: N-(2-methoxyethyl)-5-{[(4-methoxyphenyl)sulfonyl]amino}-2-piperazinonicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0080
N-(2-methoxyethyl)-5-{[(4-methoxyphenyl)sulfonyl]amino}-2-piperazinonicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0080

Molecular Formula

C20H27N5O5S (C20 H27 N5 O5 S)

Compound Name

N-(2-methoxyethyl)-5-{[(4-methoxyphenyl)sulfonyl]amino}-2-piperazinonicotinamide

IUPAC name

5-(4-methoxybenzenesulfonamido)-N-(2-methoxyethyl)-2-(piperazin-1-yl)pyridine-3-carboxamide

SMILES

COCCNC(c1cc(NS(c(cc2)ccc2OC)(=O)=O)cnc1N1CCNCC1)=O

InChI

InChI=1S/C20H27N5O5S/c1-29-12-9-22-20(26)18-13-15(14-23-19(18)25-10-7-21-8-11-25)24-31(27,28)17-5-3-16(30-2)4-6-17/h3-6,13-14,21,24H,7-12H2,1-2H3,(H,22,26)

InChI Key

NTSHVQUEWIFCEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247295

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

449.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.376

Distribution Coefficient, logD

-0.102

Water Solubility, LogSw

-2.55

Polar Surface Area

105.784

Acid Dissociation Constant (pKa)

8.85

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L346-0080 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L346-0080 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0080?
Check Price and Availability of L346-0080, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L346-0080 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0080
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0080
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0080 available by request