L346-0117 Screening compound: N-cyclohexyl-5-[(phenylsulfonyl)amino]-2-piperazinonicotinamide

L346-0117 Screening compound: N-cyclohexyl-5-[(phenylsulfonyl)amino]-2-piperazinonicotinamide
L346-0117 Screening compound: N-cyclohexyl-5-[(phenylsulfonyl)amino]-2-piperazinonicotinamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0117
N-cyclohexyl-5-[(phenylsulfonyl)amino]-2-piperazinonicotinamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0117

Molecular Formula

C22H29N5O3S (C22 H29 N5 O3 S)

Compound Name

N-cyclohexyl-5-[(phenylsulfonyl)amino]-2-piperazinonicotinamide

IUPAC name

5-benzenesulfonamido-N-cyclohexyl-2-(piperazin-1-yl)pyridine-3-carboxamide

SMILES

O=C(c1cc(NS(c2ccccc2)(=O)=O)cnc1N1CCNCC1)NC1CCCCC1

InChI

InChI=1S/C22H29N5O3S/c28-22(25-17-7-3-1-4-8-17)20-15-18(16-24-21(20)27-13-11-23-12-14-27)26-31(29,30)19-9-5-2-6-10-19/h2,5-6,9-10,15-17,23,26H,1,3-4,7-8,11-14H2,(H,25,28)

InChI Key

WQTCBQASQMXXIS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247308

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

443.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.059

Distribution Coefficient, logD

1.581

Water Solubility, LogSw

-3.55

Polar Surface Area

89.510

Acid Dissociation Constant (pKa)

7.84

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.46

L346-0117 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L346-0117 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0117?
Check Price and Availability of L346-0117, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L346-0117 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0117
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0117
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0117 available by request