L346-0185 Screening compound: N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide

L346-0185 Screening compound: N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide
L346-0185 Screening compound: N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0185
N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0185

Molecular Formula

C17H27N5O3S (C17 H27 N5 O3 S)

Compound Name

N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide

IUPAC name

N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]methanesulfonamide

SMILES

CC(CC1)CCN1C(c1cc(NS(C)(=O)=O)cnc1N1CCNCC1)=O

InChI

InChI=1S/C17H27N5O3S/c1-13-3-7-22(8-4-13)17(23)15-11-14(20-26(2,24)25)12-19-16(15)21-9-5-18-6-10-21/h11-13,18,20H,3-10H2,1-2H3

InChI Key

YAANGJCXSADUOA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247323

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

381.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.653

Distribution Coefficient, logD

-0.825

Water Solubility, LogSw

-2.39

Polar Surface Area

83.238

Acid Dissociation Constant (pKa)

9.19

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

64.70

L346-0185 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L346-0185 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0185?
Check Price and Availability of L346-0185, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L346-0185 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0185
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0185
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0185 available by request