L346-0381 Screening compound: N-butyl-5-(3,4-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide

L346-0381 Screening compound: N-butyl-5-(3,4-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide
L346-0381 Screening compound: N-butyl-5-(3,4-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0381
N-butyl-5-(3,4-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0381

Molecular Formula

C22H31N5O3S (C22 H31 N5 O3 S)

Compound Name

N-butyl-5-(3,4-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide

IUPAC name

N-butyl-5-(34-dimethylbenzenesulfonamido)-2-(piperazin-1-yl)pyridine-3-carboxamide

SMILES

CCCCNC(c1cc(NS(c2cc(C)c(C)cc2)(=O)=O)cnc1N1CCNCC1)=O

InChI

InChI=1S/C22H31N5O3S/c1-4-5-8-24-22(28)20-14-18(15-25-21(20)27-11-9-23-10-12-27)26-31(29,30)19-7-6-16(2)17(3)13-19/h6-7,13-15,23,26H,4-5,8-12H2,1-3H3,(H,24,28)

InChI Key

MMWHJSFEMYVGCK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247403

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

445.59

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.642

Distribution Coefficient, logD

2.164

Water Solubility, LogSw

-3.68

Polar Surface Area

89.898

Acid Dissociation Constant (pKa)

7.84

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

L346-0381 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L346-0381 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0381?
Check Price and Availability of L346-0381, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L346-0381 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0381
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0381
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0381 available by request