L346-0580 Screening compound: 3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide

L346-0580 Screening compound: 3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide
L346-0580 Screening compound: 3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L346-0580
3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L346-0580

Molecular Formula

C23H31N5O4S (C23 H31 N5 O4 S)

Compound Name

3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide

IUPAC name

3-methoxy-N-[5-(4-methylpiperidine-1-carbonyl)-6-(piperazin-1-yl)pyridin-3-yl]benzene-1-sulfonamide

SMILES

CC(CC1)CCN1C(c1cc(NS(c2cc(OC)ccc2)(=O)=O)cnc1N1CCNCC1)=O

InChI

InChI=1S/C23H31N5O4S/c1-17-6-10-28(11-7-17)23(29)21-14-18(16-25-22(21)27-12-8-24-9-13-27)26-33(30,31)20-5-3-4-19(15-20)32-2/h3-5,14-17,24,26H,6-13H2,1-2H3

InChI Key

JPFZFQMTJMVUST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247476

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

473.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.373

Distribution Coefficient, logD

0.895

Water Solubility, LogSw

-2.95

Polar Surface Area

89.564

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

8.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.80

L346-0580 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L346-0580 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L346-0580?
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What is the minimum amount of L346-0580 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L346-0580
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L346-0580
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L346-0580 available by request