L350-0821 Screening compound: 4-[3-(tert-butylamino)-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl]-2-methoxyphenol

L350-0821 Screening compound: 4-[3-(tert-butylamino)-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl]-2-methoxyphenol
L350-0821 Screening compound: 4-[3-(tert-butylamino)-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl]-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound L350-0821
4-[3-(tert-butylamino)-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl]-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L350-0821

Molecular Formula

C21H23N3O2S (C21 H23 N3 O2 S)

Compound Name

4-[3-(tert-butylamino)-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl]-2-methoxyphenol

IUPAC name

4-[3-(tert-butylamino)-10-methyl-7-thia-25-diazatricyclo[6.4.0.0^{26}]dodeca-1(8)35911-pentaen-4-yl]-2-methoxyphenol

SMILES

CC(C)(C)Nc1c(-c(cc2)cc(OC)c2O)nc2sc(cc(C)cc3)c3n12

InChI

InChI=1S/C21H23N3O2S/c1-12-6-8-14-17(10-12)27-20-22-18(19(24(14)20)23-21(2,3)4)13-7-9-15(25)16(11-13)26-5/h6-11,23,25H,1-5H3

InChI Key

MPSBIUJQMKMPLZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247661

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.5

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.137

Distribution Coefficient, logD

4.455

Water Solubility, LogSw

-4.86

Polar Surface Area

42.423

Acid Dissociation Constant (pKa)

8.99

Base Dissociation Constant (pKb)

7.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L350-0821 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L350-0821 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L350-0821?
Check Price and Availability of L350-0821, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L350-0821 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L350-0821
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L350-0821
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L350-0821 available by request