L350-0881 Screening compound: 4-{3-[(3-isopropoxypropyl)amino]-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl}phenol

L350-0881 Screening compound: 4-{3-[(3-isopropoxypropyl)amino]-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl}phenol
L350-0881 Screening compound: 4-{3-[(3-isopropoxypropyl)amino]-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl}phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound L350-0881
4-{3-[(3-isopropoxypropyl)amino]-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl}phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L350-0881

Molecular Formula

C22H25N3O2S (C22 H25 N3 O2 S)

Compound Name

4-{3-[(3-isopropoxypropyl)amino]-7-methylimidazo[2,1-b][1,3]benzothiazol-2-yl}phenol

IUPAC name

4-(10-methyl-3-{[3-(propan-2-yloxy)propyl]amino}-7-thia-25-diazatricyclo[6.4.0.0^{26}]dodeca-1(8)35911-pentaen-4-yl)phenol

SMILES

CC(C)OCCCNc1c(-c(cc2)ccc2O)nc2sc(cc(C)cc3)c3n12

InChI

InChI=1S/C22H25N3O2S/c1-14(2)27-12-4-11-23-21-20(16-6-8-17(26)9-7-16)24-22-25(21)18-10-5-15(3)13-19(18)28-22/h5-10,13-14,23,26H,4,11-12H2,1-3H3

InChI Key

HFGHSSOHATVEFD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247662

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.53

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.844

Distribution Coefficient, logD

4.824

Water Solubility, LogSw

-4.38

Polar Surface Area

44.080

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

5.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L350-0881 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L350-0881 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L350-0881?
Check Price and Availability of L350-0881, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L350-0881 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L350-0881
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L350-0881
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L350-0881 available by request