L351-0254 Screening compound: 2-(4-chlorophenyl)-5-{[(4-fluorobenzyl)(methyl)amino]methyl}pyrazolo[1,5-a]pyrimidin-7(1H)-one

L351-0254 Screening compound: 2-(4-chlorophenyl)-5-{[(4-fluorobenzyl)(methyl)amino]methyl}pyrazolo[1,5-a]pyrimidin-7(1H)-one
L351-0254 Screening compound: 2-(4-chlorophenyl)-5-{[(4-fluorobenzyl)(methyl)amino]methyl}pyrazolo[1,5-a]pyrimidin-7(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L351-0254
2-(4-chlorophenyl)-5-{[(4-fluorobenzyl)(methyl)amino]methyl}pyrazolo[1,5-a]pyrimidin-7(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L351-0254

Molecular Formula

C21H18ClFN4O (C21 H18 ClFN4 O)

Compound Name

2-(4-chlorophenyl)-5-{[(4-fluorobenzyl)(methyl)amino]methyl}pyrazolo[1,5-a]pyrimidin-7(1H)-one

IUPAC name

2-(4-chlorophenyl)-5-({[(4-fluorophenyl)methyl](methyl)amino}methyl)-1H7H-pyrazolo[15-a]pyrimidin-7-one

SMILES

CN(Cc(cc1)ccc1F)CC(N=C1N2NC(c(cc3)ccc3Cl)=C1)=CC2=O

InChI

InChI=1S/C21H18ClFN4O/c1-26(12-14-2-8-17(23)9-3-14)13-18-10-21(28)27-20(24-18)11-19(25-27)15-4-6-16(22)7-5-15/h2-11,25H,12-13H2,1H3

InChI Key

QSFRPMNTGYGQIO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.85

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.479

Distribution Coefficient, logD

3.407

Water Solubility, LogSw

-4.09

Polar Surface Area

45.018

Acid Dissociation Constant (pKa)

8.43

Base Dissociation Constant (pKb)

6.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.29

L351-0254 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Neurotransmitter Transporter Inhibitors Library (11024 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
Targets:
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with L351-0254 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L351-0254?
Check Price and Availability of L351-0254, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L351-0254 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L351-0254
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L351-0254
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L351-0254 available by request