L356-0066 Screening compound: 1-(2,4-difluorophenyl)-3-(2-methanesulfonamido-1,3-benzothiazol-5-yl)urea

L356-0066 Screening compound: 1-(2,4-difluorophenyl)-3-(2-methanesulfonamido-1,3-benzothiazol-5-yl)urea
L356-0066 Screening compound: 1-(2,4-difluorophenyl)-3-(2-methanesulfonamido-1,3-benzothiazol-5-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L356-0066
1-(2,4-difluorophenyl)-3-(2-methanesulfonamido-1,3-benzothiazol-5-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L356-0066

Molecular Formula

C15H12F2N4O3S2 (C15 H12 F2 N4 O3 S2)

Compound Name

1-(2,4-difluorophenyl)-3-(2-methanesulfonamido-1,3-benzothiazol-5-yl)urea

IUPAC name

1-(24-difluorophenyl)-3-(2-methanesulfonamido-13-benzothiazol-5-yl)urea

SMILES

CS(Nc1nc(cc(cc2)NC(Nc(ccc(F)c3)c3F)=O)c2s1)(=O)=O

InChI

InChI=1S/C15H12F2N4O3S2/c1-26(23,24)21-15-20-12-7-9(3-5-13(12)25-15)18-14(22)19-11-4-2-8(16)6-10(11)17/h2-7H,1H3,(H,20,21)(H2,18,19,22)

InChI Key

XJMLTVXSQQAXLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124845

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.532

Distribution Coefficient, logD

3.400

Water Solubility, LogSw

-3.90

Polar Surface Area

83.472

Acid Dissociation Constant (pKa)

7.85

Base Dissociation Constant (pKb)

-1.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

L356-0066 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L356-0066 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L356-0066?
Check Price and Availability of L356-0066, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L356-0066 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L356-0066
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L356-0066
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L356-0066 available by request