L362-0783 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

L362-0783 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea
L362-0783 Screening compound: 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L362-0783
3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L362-0783

Molecular Formula

C26H26N4O3 (C26 H26 N4 O3)

Compound Name

3-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

IUPAC name

3-(23-dihydro-14-benzodioxin-6-yl)-1-{3-[2-(1-ethyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}urea

SMILES

CCn1c(cccc2)c2nc1CCc1cccc(NC(Nc(cc2)cc3c2OCCO3)=O)c1

InChI

InChI=1S/C26H26N4O3/c1-2-30-22-9-4-3-8-21(22)29-25(30)13-10-18-6-5-7-19(16-18)27-26(31)28-20-11-12-23-24(17-20)33-15-14-32-23/h3-9,11-12,16-17H,2,10,13-15H2,1H3,(H2,27,28,31)

InChI Key

NPJZTBSYNMJBRQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124939

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.857

Distribution Coefficient, logD

4.840

Water Solubility, LogSw

-4.54

Polar Surface Area

58.994

Acid Dissociation Constant (pKa)

13.05

Base Dissociation Constant (pKb)

5.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.10

L362-0783 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L362-0783 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L362-0783?
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What is the minimum amount of L362-0783 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L362-0783
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L362-0783
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L362-0783 available by request