L362-1395 Screening compound: 1-{3-[2-(1-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea

L362-1395 Screening compound: 1-{3-[2-(1-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea
L362-1395 Screening compound: 1-{3-[2-(1-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L362-1395
1-{3-[2-(1-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L362-1395

Molecular Formula

C24H21F3N4O (C24 H21 F3 N4 O)

Compound Name

1-{3-[2-(1-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea

IUPAC name

1-{3-[2-(1-methyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}-3-[3-(trifluoromethyl)phenyl]urea

SMILES

Cn1c(cccc2)c2nc1CCc1cccc(NC(Nc2cccc(C(F)(F)F)c2)=O)c1

InChI

InChI=1S/C24H21F3N4O/c1-31-21-11-3-2-10-20(21)30-22(31)13-12-16-6-4-8-18(14-16)28-23(32)29-19-9-5-7-17(15-19)24(25,26)27/h2-11,14-15H,12-13H2,1H3,(H2,28,29,32)

InChI Key

XUQXAFDOEGKEGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124964

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.45

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.288

Distribution Coefficient, logD

6.163

Water Solubility, LogSw

-5.67

Polar Surface Area

44.256

Acid Dissociation Constant (pKa)

11.94

Base Dissociation Constant (pKb)

6.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L362-1395 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

PI3K-Targeted Library (17255 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Phosphatases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L362-1395 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L362-1395?
Check Price and Availability of L362-1395, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L362-1395 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L362-1395
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L362-1395
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L362-1395 available by request