L362-2345 Screening compound: 3-(3,5-dimethylphenyl)-1-{3-[2-(1-propyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

L362-2345 Screening compound: 3-(3,5-dimethylphenyl)-1-{3-[2-(1-propyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea
L362-2345 Screening compound: 3-(3,5-dimethylphenyl)-1-{3-[2-(1-propyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L362-2345
3-(3,5-dimethylphenyl)-1-{3-[2-(1-propyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L362-2345

Molecular Formula

C27H30N4O (C27 H30 N4 O)

Compound Name

3-(3,5-dimethylphenyl)-1-{3-[2-(1-propyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

IUPAC name

3-(35-dimethylphenyl)-1-{3-[2-(1-propyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}urea

SMILES

CCCn1c(cccc2)c2nc1CCc1cccc(NC(Nc2cc(C)cc(C)c2)=O)c1

InChI

InChI=1S/C27H30N4O/c1-4-14-31-25-11-6-5-10-24(25)30-26(31)13-12-21-8-7-9-22(18-21)28-27(32)29-23-16-19(2)15-20(3)17-23/h5-11,15-18H,4,12-14H2,1-3H3,(H2,28,29,32)

InChI Key

LEIVOHRPOMEDFO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15124975

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.56

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

7.035

Distribution Coefficient, logD

7.030

Water Solubility, LogSw

-5.65

Polar Surface Area

43.425

Acid Dissociation Constant (pKa)

14.71

Base Dissociation Constant (pKb)

5.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

L362-2345 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L362-2345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L362-2345?
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What is the minimum amount of L362-2345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L362-2345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L362-2345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L362-2345 available by request