L362-3427 Screening compound: 3-(3,5-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

L362-3427 Screening compound: 3-(3,5-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea
L362-3427 Screening compound: 3-(3,5-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L362-3427
3-(3,5-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L362-3427

Molecular Formula

C30H28N4O3 (C30 H28 N4 O3)

Compound Name

3-(3,5-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

IUPAC name

3-(35-dimethoxyphenyl)-1-{3-[2-(1-phenyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}urea

SMILES

COc1cc(NC(Nc2cc(CCc3nc(cccc4)c4n3-c3ccccc3)ccc2)=O)cc(OC)c1

InChI

InChI=1S/C30H28N4O3/c1-36-25-18-23(19-26(20-25)37-2)32-30(35)31-22-10-8-9-21(17-22)15-16-29-33-27-13-6-7-14-28(27)34(29)24-11-4-3-5-12-24/h3-14,17-20H,15-16H2,1-2H3,(H2,31,32,35)

InChI Key

UOAFFFGSJPJIHI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

492.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

6.757

Distribution Coefficient, logD

6.705

Water Solubility, LogSw

-5.71

Polar Surface Area

59.006

Acid Dissociation Constant (pKa)

12.39

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

L362-3427 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L362-3427 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L362-3427?
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What is the minimum amount of L362-3427 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L362-3427
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L362-3427
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L362-3427 available by request