L364-0128 Screening compound: 4-[5-(2,4-difluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-methylbenzamide

L364-0128 Screening compound: 4-[5-(2,4-difluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-methylbenzamide
L364-0128 Screening compound: 4-[5-(2,4-difluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L364-0128
4-[5-(2,4-difluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L364-0128

Molecular Formula

C22H18F2N4O3S (C22 H18 F2 N4 O3 S)

Compound Name

4-[5-(2,4-difluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-methylbenzamide

IUPAC name

4-[5-(24-difluorobenzenesulfonamido)-1-methyl-1H-13-benzodiazol-2-yl]-N-methylbenzamide

SMILES

CNC(c(cc1)ccc1-c1nc(cc(cc2)NS(c(ccc(F)c3)c3F)(=O)=O)c2n1C)=O

InChI

InChI=1S/C22H18F2N4O3S/c1-25-22(29)14-5-3-13(4-6-14)21-26-18-12-16(8-9-19(18)28(21)2)27-32(30,31)20-10-7-15(23)11-17(20)24/h3-12,27H,1-2H3,(H,25,29)

InChI Key

LVAMEJGQUSBWQW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247854

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.571

Distribution Coefficient, logD

3.485

Water Solubility, LogSw

-4.02

Polar Surface Area

76.462

Acid Dissociation Constant (pKa)

8.08

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

L364-0128 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L364-0128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L364-0128?
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What is the minimum amount of L364-0128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L364-0128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L364-0128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L364-0128 available by request