L364-0277 Screening compound: 4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-(propan-2-yl)benzamide

L364-0277 Screening compound: 4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-(propan-2-yl)benzamide
L364-0277 Screening compound: 4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-(propan-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L364-0277
4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-(propan-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L364-0277

Molecular Formula

C24H23FN4O3S (C24 H23 FN4 O3 S)

Compound Name

4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-1,3-benzodiazol-2-yl]-N-(propan-2-yl)benzamide

IUPAC name

4-[5-(4-fluorobenzenesulfonamido)-1-methyl-1H-13-benzodiazol-2-yl]-N-(propan-2-yl)benzamide

SMILES

CC(C)NC(c(cc1)ccc1-c1nc(cc(cc2)NS(c(cc3)ccc3F)(=O)=O)c2n1C)=O

InChI

InChI=1S/C24H23FN4O3S/c1-15(2)26-24(30)17-6-4-16(5-7-17)23-27-21-14-19(10-13-22(21)29(23)3)28-33(31,32)20-11-8-18(25)9-12-20/h4-15,28H,1-3H3,(H,26,30)

InChI Key

GZTJNYSKKMWLAC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247892

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.285

Distribution Coefficient, logD

4.199

Water Solubility, LogSw

-4.34

Polar Surface Area

75.286

Acid Dissociation Constant (pKa)

8.08

Base Dissociation Constant (pKb)

5.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L364-0277 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with L364-0277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L364-0277?
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What is the minimum amount of L364-0277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L364-0277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L364-0277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L364-0277 available by request