L365-0110 Screening compound: 3-(3,4-dimethylphenyl)-1-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

L365-0110 Screening compound: 3-(3,4-dimethylphenyl)-1-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea
L365-0110 Screening compound: 3-(3,4-dimethylphenyl)-1-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L365-0110
3-(3,4-dimethylphenyl)-1-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L365-0110

Molecular Formula

C25H26N4O (C25 H26 N4 O)

Compound Name

3-(3,4-dimethylphenyl)-1-{4-[2-(5-methyl-1H-1,3-benzodiazol-2-yl)ethyl]phenyl}urea

IUPAC name

3-(34-dimethylphenyl)-1-{4-[2-(5-methyl-1H-13-benzodiazol-2-yl)ethyl]phenyl}urea

SMILES

Cc(cc1)cc2c1[nH]c(CCc(cc1)ccc1NC(Nc1cc(C)c(C)cc1)=O)n2

InChI

InChI=1S/C25H26N4O/c1-16-4-12-22-23(14-16)29-24(28-22)13-8-19-6-10-20(11-7-19)26-25(30)27-21-9-5-17(2)18(3)15-21/h4-7,9-12,14-15H,8,13H2,1-3H3,(H,28,29)(H2,26,27,30)

InChI Key

CEDIHKAMGIWSGL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27247931

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.51

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.919

Distribution Coefficient, logD

6.903

Water Solubility, LogSw

-5.55

Polar Surface Area

52.551

Acid Dissociation Constant (pKa)

13.72

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L365-0110 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Targeted Diversity Library (40567 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with L365-0110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L365-0110?
Check Price and Availability of L365-0110, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L365-0110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L365-0110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L365-0110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L365-0110 available by request