L366-0316 Screening compound: 3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-1,3-benzothiazol-6-yl]urea

L366-0316 Screening compound: 3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-1,3-benzothiazol-6-yl]urea
L366-0316 Screening compound: 3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-1,3-benzothiazol-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L366-0316
3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-1,3-benzothiazol-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L366-0316

Molecular Formula

C19H22N4O4S2 (C19 H22 N4 O4 S2)

Compound Name

3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-1,3-benzothiazol-6-yl]urea

IUPAC name

3-(3-methoxypropyl)-1-[2-(4-methylbenzenesulfonamido)-13-benzothiazol-6-yl]urea

SMILES

Cc(cc1)ccc1S(Nc1nc(ccc(NC(NCCCOC)=O)c2)c2s1)(=O)=O

InChI

InChI=1S/C19H22N4O4S2/c1-13-4-7-15(8-5-13)29(25,26)23-19-22-16-9-6-14(12-17(16)28-19)21-18(24)20-10-3-11-27-2/h4-9,12H,3,10-11H2,1-2H3,(H,22,23)(H2,20,21,24)

InChI Key

VSBBDSQKSHYXAA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125281

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.762

Distribution Coefficient, logD

3.361

Water Solubility, LogSw

-3.84

Polar Surface Area

92.730

Acid Dissociation Constant (pKa)

7.22

Base Dissociation Constant (pKb)

0.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

L366-0316 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L366-0316 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L366-0316?
Check Price and Availability of L366-0316, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L366-0316 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L366-0316
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L366-0316
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L366-0316 available by request