L367-0661 Screening compound: 4-[2-(benzylamino)pyrimidin-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide

L367-0661 Screening compound: 4-[2-(benzylamino)pyrimidin-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide
L367-0661 Screening compound: 4-[2-(benzylamino)pyrimidin-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L367-0661
4-[2-(benzylamino)pyrimidin-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L367-0661

Molecular Formula

C28H26N4O (C28 H26 N4 O)

Compound Name

4-[2-(benzylamino)pyrimidin-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide

IUPAC name

4-[2-(benzylamino)pyrimidin-5-yl]-N-(1234-tetrahydronaphthalen-1-yl)benzamide

SMILES

O=C(c(cc1)ccc1-c1cnc(NCc2ccccc2)nc1)NC(CCC1)c2c1cccc2

InChI

InChI=1S/C28H26N4O/c33-27(32-26-12-6-10-22-9-4-5-11-25(22)26)23-15-13-21(14-16-23)24-18-30-28(31-19-24)29-17-20-7-2-1-3-8-20/h1-5,7-9,11,13-16,18-19,26H,6,10,12,17H2,(H,32,33)(H,29,30,31)/t26-/m0/s1

InChI Key

ZEYYQHOGWWSFTA-SANMLTNESA-N

MDL Number (MFCD)

MFCD27248115

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.926

Distribution Coefficient, logD

4.926

Water Solubility, LogSw

-4.94

Polar Surface Area

55.207

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

2.75

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.90

L367-0661 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with L367-0661 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L367-0661?
Check Price and Availability of L367-0661, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L367-0661 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L367-0661
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L367-0661
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L367-0661 available by request