L368-0210 Screening compound: N-(3-CHLORO-4-FLUOROPHENYL)-3-[2-(PIPERIDIN-1-YL)PYRIMIDIN-5-YL]BENZAMIDE

L368-0210 Screening compound: N-(3-CHLORO-4-FLUOROPHENYL)-3-[2-(PIPERIDIN-1-YL)PYRIMIDIN-5-YL]BENZAMIDE
L368-0210 Screening compound: N-(3-CHLORO-4-FLUOROPHENYL)-3-[2-(PIPERIDIN-1-YL)PYRIMIDIN-5-YL]BENZAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L368-0210
N-(3-CHLORO-4-FLUOROPHENYL)-3-[2-(PIPERIDIN-1-YL)PYRIMIDIN-5-YL]BENZAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L368-0210

Molecular Formula

C22H20ClFN4O (C22 H20 ClFN4 O)

Compound Name

N-(3-CHLORO-4-FLUOROPHENYL)-3-[2-(PIPERIDIN-1-YL)PYRIMIDIN-5-YL]BENZAMIDE

IUPAC name

n/a

SMILES

O=C(c1cc(-c2cnc(N3CCCCC3)nc2)ccc1)Nc(cc1)cc(Cl)c1F

InChI

InChI=1S/C22H20ClFN4O/c23-19-12-18(7-8-20(19)24)27-21(29)16-6-4-5-15(11-16)17-13-25-22(26-14-17)28-9-2-1-3-10-28/h4-8,11-14H,1-3,9-10H2,(H,27,29)

InChI Key

KQQVFOFJIWQAHK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27248237

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.014

Distribution Coefficient, logD

4.922

Water Solubility, LogSw

-5.32

Polar Surface Area

45.052

Acid Dissociation Constant (pKa)

8.03

Base Dissociation Constant (pKb)

9.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L368-0210 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L368-0210 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L368-0210?
Check Price and Availability of L368-0210, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L368-0210 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L368-0210
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L368-0210
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L368-0210 available by request