L368-0224 Screening compound: N-(2,4-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide

L368-0224 Screening compound: N-(2,4-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide
L368-0224 Screening compound: N-(2,4-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L368-0224
N-(2,4-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L368-0224

Molecular Formula

C24H26N4O3 (C24 H26 N4 O3)

Compound Name

N-(2,4-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide

IUPAC name

N-(24-dimethoxyphenyl)-3-[2-(piperidin-1-yl)pyrimidin-5-yl]benzamide

SMILES

COc(cc1)cc(OC)c1NC(c1cc(-c2cnc(N3CCCCC3)nc2)ccc1)=O

InChI

InChI=1S/C24H26N4O3/c1-30-20-9-10-21(22(14-20)31-2)27-23(29)18-8-6-7-17(13-18)19-15-25-24(26-16-19)28-11-4-3-5-12-28/h6-10,13-16H,3-5,11-12H2,1-2H3,(H,27,29)

InChI Key

HOYUCMUQAZBXLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27248245

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.227

Distribution Coefficient, logD

4.226

Water Solubility, LogSw

-4.25

Polar Surface Area

59.528

Acid Dissociation Constant (pKa)

9.93

Base Dissociation Constant (pKb)

9.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L368-0224 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L368-0224 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L368-0224?
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What is the minimum amount of L368-0224 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L368-0224
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L368-0224
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L368-0224 available by request