L370-0528 Screening compound: 4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide

L370-0528 Screening compound: 4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide
L370-0528 Screening compound: 4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L370-0528
4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L370-0528

Molecular Formula

C26H23FN4O (C26 H23 FN4 O)

Compound Name

4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide

IUPAC name

4-{[5-(3-fluorophenyl)pyrimidin-2-yl]amino}-N-[1-(4-methylphenyl)ethyl]benzamide

SMILES

CC(c1ccc(C)cc1)NC(c(cc1)ccc1Nc(nc1)ncc1-c1cccc(F)c1)=O

InChI

InChI=1S/C26H23FN4O/c1-17-6-8-19(9-7-17)18(2)30-25(32)20-10-12-24(13-11-20)31-26-28-15-22(16-29-26)21-4-3-5-23(27)14-21/h3-16,18H,1-2H3,(H,30,32)(H,28,29,31)/t18-/m0/s1

InChI Key

BVIPXXBLBNTHRF-SFHVURJKSA-N

MDL Number (MFCD)

MFCD15125453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.49

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.152

Distribution Coefficient, logD

5.152

Water Solubility, LogSw

-4.90

Polar Surface Area

53.205

Acid Dissociation Constant (pKa)

11.47

Base Dissociation Constant (pKb)

2.34

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

11.50

L370-0528 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CORONAVIRUS Library (20774 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with L370-0528 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L370-0528?
Check Price and Availability of L370-0528, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L370-0528 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L370-0528
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L370-0528
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L370-0528 available by request