L371-0006 Screening compound: N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

L371-0006 Screening compound: N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
L371-0006 Screening compound: N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L371-0006
N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L371-0006

Molecular Formula

C29H27N5O2 (C29 H27 N5 O2)

Compound Name

N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

IUPAC name

N-benzyl-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[34-b]pyridine-5-carboxamide

SMILES

Cc(c1c2ncc(C(NCc3ccccc3)=O)c1NCc(cc1)ccc1OC)nn2-c1ccccc1

InChI

InChI=1S/C29H27N5O2/c1-20-26-27(30-17-22-13-15-24(36-2)16-14-22)25(29(35)32-18-21-9-5-3-6-10-21)19-31-28(26)34(33-20)23-11-7-4-8-12-23/h3-16,19H,17-18H2,1-2H3,(H,30,31)(H,32,35)

InChI Key

KHMNNGSFQSKHBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125470

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

477.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.070

Distribution Coefficient, logD

4.055

Water Solubility, LogSw

-4.40

Polar Surface Area

64.952

Acid Dissociation Constant (pKa)

12.63

Base Dissociation Constant (pKb)

5.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.80

L371-0006 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Glucocorticoid receptors Library (4806 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Proteases
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L371-0006 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L371-0006?
Check Price and Availability of L371-0006, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L371-0006 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L371-0006
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L371-0006
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L371-0006 available by request