L371-0013 Screening compound: N-(2,4-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

L371-0013 Screening compound: N-(2,4-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide
L371-0013 Screening compound: N-(2,4-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L371-0013
N-(2,4-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L371-0013

Molecular Formula

C28H23F2N5O2 (C28 H23 F2 N5 O2)

Compound Name

N-(2,4-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide

IUPAC name

N-(24-difluorophenyl)-4-{[(4-methoxyphenyl)methyl]amino}-3-methyl-1-phenyl-1H-pyrazolo[34-b]pyridine-5-carboxamide

SMILES

Cc(c1c2ncc(C(Nc(ccc(F)c3)c3F)=O)c1NCc(cc1)ccc1OC)nn2-c1ccccc1

InChI

InChI=1S/C28H23F2N5O2/c1-17-25-26(31-15-18-8-11-21(37-2)12-9-18)22(28(36)33-24-13-10-19(29)14-23(24)30)16-32-27(25)35(34-17)20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,31,32)(H,33,36)

InChI Key

HXIARUHFIIKKTP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.220

Distribution Coefficient, logD

4.182

Water Solubility, LogSw

-4.44

Polar Surface Area

62.932

Acid Dissociation Constant (pKa)

8.46

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.70

L371-0013 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L371-0013 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L371-0013?
Check Price and Availability of L371-0013, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L371-0013 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L371-0013
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L371-0013
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L371-0013 available by request