L372-0044 Screening compound: N,1-bis(4-fluorophenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide

L372-0044 Screening compound: N,1-bis(4-fluorophenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide
L372-0044 Screening compound: N,1-bis(4-fluorophenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L372-0044
N,1-bis(4-fluorophenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L372-0044

Molecular Formula

C22H16F2N2O3 (C22 H16 F2 N2 O3)

Compound Name

N,1-bis(4-fluorophenyl)-2,5-dioxo-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide

IUPAC name

N1-bis(4-fluorophenyl)-25-dioxo-125678-hexahydroquinoline-3-carboxamide

SMILES

O=C(C1=CC(C(CCC2)=O)=C2N(c(cc2)ccc2F)C1=O)Nc(cc1)ccc1F

InChI

InChI=1S/C22H16F2N2O3/c23-13-4-8-15(9-5-13)25-21(28)18-12-17-19(2-1-3-20(17)27)26(22(18)29)16-10-6-14(24)7-11-16/h4-12H,1-3H2,(H,25,28)

InChI Key

NSZURFWVSSUSDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125531

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.947

Distribution Coefficient, logD

2.682

Water Solubility, LogSw

-3.69

Polar Surface Area

51.671

Acid Dissociation Constant (pKa)

7.48

Base Dissociation Constant (pKb)

-4.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.64

L372-0044 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L372-0044 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L372-0044?
Check Price and Availability of L372-0044, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L372-0044 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L372-0044
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L372-0044
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L372-0044 available by request