L372-0899 Screening compound: N-(2-methoxyphenyl)-2,5-dioxo-1-[4-(trifluoromethyl)phenyl]-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

L372-0899 Screening compound: N-(2-methoxyphenyl)-2,5-dioxo-1-[4-(trifluoromethyl)phenyl]-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide
L372-0899 Screening compound: N-(2-methoxyphenyl)-2,5-dioxo-1-[4-(trifluoromethyl)phenyl]-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L372-0899
N-(2-methoxyphenyl)-2,5-dioxo-1-[4-(trifluoromethyl)phenyl]-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L372-0899

Molecular Formula

C24H19F3N2O4 (C24 H19 F3 N2 O4)

Compound Name

N-(2-methoxyphenyl)-2,5-dioxo-1-[4-(trifluoromethyl)phenyl]-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

IUPAC name

N-(2-methoxyphenyl)-25-dioxo-1-[4-(trifluoromethyl)phenyl]-125678-hexahydroquinoline-3-carboxamide

SMILES

COc(cccc1)c1NC(C1=CC(C(CCC2)=O)=C2N(c2ccc(C(F)(F)F)cc2)C1=O)=O

InChI

InChI=1S/C24H19F3N2O4/c1-33-21-8-3-2-5-18(21)28-22(31)17-13-16-19(6-4-7-20(16)30)29(23(17)32)15-11-9-14(10-12-15)24(25,26)27/h2-3,5,8-13H,4,6-7H2,1H3,(H,28,31)

InChI Key

XDJCUWPWQFAULE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125714

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.713

Distribution Coefficient, logD

3.574

Water Solubility, LogSw

-4.31

Polar Surface Area

58.604

Acid Dissociation Constant (pKa)

7.83

Base Dissociation Constant (pKb)

-3.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.80

L372-0899 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L372-0899 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L372-0899?
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What is the minimum amount of L372-0899 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L372-0899
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L372-0899
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L372-0899 available by request