L378-0329 Screening compound: N~1~-(2,5-dimethylphenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetraazol-5-yl]tetrahydro-1(2H)-pyrazinecarboxamide

L378-0329 Screening compound: N~1~-(2,5-dimethylphenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetraazol-5-yl]tetrahydro-1(2H)-pyrazinecarboxamide
L378-0329 Screening compound: N~1~-(2,5-dimethylphenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetraazol-5-yl]tetrahydro-1(2H)-pyrazinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L378-0329
N~1~-(2,5-dimethylphenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetraazol-5-yl]tetrahydro-1(2H)-pyrazinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L378-0329

Molecular Formula

C22H27N7O (C22 H27 N7 O)

Compound Name

N~1~-(2,5-dimethylphenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetraazol-5-yl]tetrahydro-1(2H)-pyrazinecarboxamide

IUPAC name

n/a

SMILES

CCc1cccc(-n2nnnc2N(CC2)CCN2C(Nc2c(C)ccc(C)c2)=O)c1

InChI

InChI=1S/C22H27N7O/c1-4-18-6-5-7-19(15-18)29-21(24-25-26-29)27-10-12-28(13-11-27)22(30)23-20-14-16(2)8-9-17(20)3/h5-9,14-15H,4,10-13H2,1-3H3,(H,23,30)

InChI Key

STRSFFWIRAGRBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.020

Distribution Coefficient, logD

4.020

Water Solubility, LogSw

-3.85

Polar Surface Area

67.151

Acid Dissociation Constant (pKa)

13.97

Base Dissociation Constant (pKb)

-1.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

L378-0329 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L378-0329 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L378-0329?
Check Price and Availability of L378-0329, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L378-0329 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L378-0329
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L378-0329
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L378-0329 available by request