L378-0346 Screening compound: N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetrazol-5-yl]piperazine-1-carboxamide

L378-0346 Screening compound: N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetrazol-5-yl]piperazine-1-carboxamide
L378-0346 Screening compound: N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetrazol-5-yl]piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L378-0346
N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetrazol-5-yl]piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L378-0346

Molecular Formula

C20H22BrN7O (C20 H22 BrN7 O)

Compound Name

N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1,2,3,4-tetrazol-5-yl]piperazine-1-carboxamide

IUPAC name

N-(3-bromophenyl)-4-[1-(3-ethylphenyl)-1H-1234-tetrazol-5-yl]piperazine-1-carboxamide

SMILES

CCc1cccc(-n2nnnc2N(CC2)CCN2C(Nc2cccc(Br)c2)=O)c1

InChI

InChI=1S/C20H22BrN7O/c1-2-15-5-3-8-18(13-15)28-19(23-24-25-28)26-9-11-27(12-10-26)20(29)22-17-7-4-6-16(21)14-17/h3-8,13-14H,2,9-12H2,1H3,(H,22,29)

InChI Key

YDFODKDWRAHZKE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125872

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.390

Distribution Coefficient, logD

4.390

Water Solubility, LogSw

-4.17

Polar Surface Area

67.849

Acid Dissociation Constant (pKa)

12.15

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

L378-0346 in Drug Discovery

Included in Screening Libraries

Bcl2-PPI Inhibitors Library (12246 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Mechanism of action:
  • PPI modulators
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L378-0346 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L378-0346?
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What is the minimum amount of L378-0346 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L378-0346
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L378-0346
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L378-0346 available by request