L380-0055 Screening compound: 4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline

L380-0055 Screening compound: 4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline
L380-0055 Screening compound: 4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L380-0055
4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L380-0055

Molecular Formula

C25H29N3OS (C25 H29 N3 OS)

Compound Name

4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline

IUPAC name

4-(4-cyclohexylpiperazine-1-carbonyl)-2-methyl-8-(thiophen-2-yl)quinoline

SMILES

Cc1cc(C(N(CC2)CCN2C2CCCCC2)=O)c(cccc2-c3cccs3)c2n1

InChI

InChI=1S/C25H29N3OS/c1-18-17-22(20-9-5-10-21(24(20)26-18)23-11-6-16-30-23)25(29)28-14-12-27(13-15-28)19-7-3-2-4-8-19/h5-6,9-11,16-17,19H,2-4,7-8,12-15H2,1H3

InChI Key

GHIKCQOWGKHTJN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15125891

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.881

Distribution Coefficient, logD

4.719

Water Solubility, LogSw

-4.82

Polar Surface Area

29.635

Acid Dissociation Constant (pKa)

28.35

Base Dissociation Constant (pKb)

7.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

L380-0055 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L380-0055 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L380-0055?
Check Price and Availability of L380-0055, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L380-0055 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L380-0055
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L380-0055
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L380-0055 available by request