L381-0932 Screening compound: 1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide

L381-0932 Screening compound: 1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide
L381-0932 Screening compound: 1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L381-0932
1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L381-0932

Molecular Formula

C22H28ClN5O2S (C22 H28 ClN5 O2 S)

Compound Name

1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide

IUPAC name

1-{6-[({[(4-chlorophenyl)methyl]carbamoyl}methyl)sulfanyl]pyridazin-3-yl}-N-(propan-2-yl)piperidine-4-carboxamide

SMILES

CC(C)NC(C(CC1)CCN1c(cc1)nnc1SCC(NCc(cc1)ccc1Cl)=O)=O

InChI

InChI=1S/C22H28ClN5O2S/c1-15(2)25-22(30)17-9-11-28(12-10-17)19-7-8-21(27-26-19)31-14-20(29)24-13-16-3-5-18(23)6-4-16/h3-8,15,17H,9-14H2,1-2H3,(H,24,29)(H,25,30)

InChI Key

IWXMWXUHONYJMN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27248764

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.02

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.005

Distribution Coefficient, logD

3.005

Water Solubility, LogSw

-3.53

Polar Surface Area

72.117

Acid Dissociation Constant (pKa)

12.79

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.50

L381-0932 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with L381-0932 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L381-0932?
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What is the minimum amount of L381-0932 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L381-0932
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L381-0932
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L381-0932 available by request